Dichloromethane → 2-(3-Methylphenyl)-3-(piperazin-1-yl)pyrazine

HRID 314126Notes

Reaction equation

HRID 314126 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][c:22]([CH3:26])[cH:23][cH:24][cH:25]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:34][CH2:35][Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][cH:16][cH:17][n:18][c:19]2-[c:20]2[cH:21][c:22]([CH3:26])[cH:23][cH:24][cH:25]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 687368123'-m-Tolyl-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-carboxylic acid t-butyl ester

Product 1

HCID 685957832-(3-Methylphenyl)-3-(piperazin-1-yl)pyrazine

Sources & evidence

ORD record
ord-de7ce98a5e5740e681d44b9f33927a57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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