HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Bromophenyl)-1,3-thiazol-2-amine hydrobromide → 4'-(2-Amino-4-thiazolyl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Bromophenyl)-1,3-thiazol-2-amine hydrobromide | HCID 2787880 | — |
| Reactant | 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide | HCID 59791521 | — |
| Product | 4'-(2-Amino-4-thiazolyl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide | HCID 9956363 | — |
Reaction Steps
Example 1 was prepared using 4-(4-bromophenyl)-2-thiazolamine monohydrobromide and 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamide (Intermediate 5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425555B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-e7d90018ed3d40209c184f4d2fd498a8 |
| Source note | uspto-grants-2008_09 |