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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 31434Generated: October 25, 2026

2-(4-bromophenyl)-1H-imidazole → 4'-(1H-Imidazol-2-yl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamide

https://huagongshe.com/reaction/31434

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-bromophenyl)-1H-imidazoleHCID 11694265—
Reactant4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzamideHCID 59791521—
Product4'-(1H-Imidazol-2-yl)-6-methyl-N-[3-(4-morpholinyl)phenyl][1,1'-biphenyl]-3-carboxamideHCID 10478297—

Reaction Steps

Example 4 was prepared using 2-(4-bromophenyl)-1H-imidazole and 4-methyl-N-[3-(4-morpholinyl)phenyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (Intermediate 5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07425555B2
Source datasetuspto-grants-2008_09
ORD IDord-40a8600da11f46238dbf229ba6b2f4b8
Source noteuspto-grants-2008_09