Methylamine → Gsk-207040

HRID 314368Notes

Reaction equation

HRID 314368 reaction equation
[CH3:26][NH2:27].[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([O:16][c:17]4[n:18][cH:19][c:20]([C:23](=[O:24])[Cl:25])[n:21][cH:22]4)[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1.[Cl:28][CH2:29][Cl:30]>>[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([O:16][c:17]4[n:18][cH:19][c:20]([C:23](=[O:24])[NH:27][CH3:26])[n:21][cH:22]4)[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1

Participants

4

Reactant 3

HCID 6329MethylamineHCID 6344DichloromethaneHCID 866032205-(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yloxy)-pyrazine-2-carbonyl chloride

Product 1

HCID 10473209Gsk-207040

Sources & evidence

ORD record
ord-32b06f4ec4be4445a30bc8cd00141054
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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