Hydrochloric Acid → 5-[4-chloro-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-nicotinic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][n:7][cH:8][c:9](-[c:11]2[c:12]([Cl:28])[c:13]3[c:14]([n:15][cH:16]2)[n:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][cH:19]3)[cH:10]1)=[O:29].[CH3:33][CH2:34][OH:35].[ClH:32].[K+:31].[OH-:30].[OH2:36]>>[O:3]=[C:4]([c:5]1[cH:6][n:7][cH:8][c:9](-[c:11]2[c:12]([Cl:28])[c:13]3[c:14]([n:15][cH:16]2)[n:17]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])[cH:18][cH:19]3)[cH:10]1)[OH:29]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-0a3c13f4524943d0a680f28100689f0a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…