2-Methylpyridine → 1,1,1-Trifluoro-4-(5-fluoro-2-methoxyphenyl)-2-(pyridin-2-ylmethyl)-4-methylpentan-2-ol
Reaction equation
[C:1]([Li:2])([CH3:3])([CH3:4])[CH3:5].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:6][c:7]1[cH:8][cH:9][cH:10][cH:11][n:12]1.[F:13][C:14]([C:15]([CH2:16][C:17]([CH3:18])([CH3:19])[c:20]1[c:21]([O:27][CH3:28])[cH:22][cH:23][c:24]([F:26])[cH:25]1)=[O:29])([F:30])[F:31]>>[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][n:12]1)[C:15]([C:14]([F:13])([F:30])[F:31])([CH2:16][C:17]([CH3:18])([CH3:19])[c:20]1[c:21]([O:27][CH3:28])[cH:22][cH:23][c:24]([F:26])[cH:25]1)[OH:29]Participants
5
Sources & evidence
- ORD record
- ord-58841fadcb2c4177baee38b9fc3c66a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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