Hydrochloric Acid → N,alpha-bis(4-fluorophenyl)-4-piperidinemethanamine
Reaction equation
[BH4-:35].[CH3:40][CH2:41][OH:42].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([C:7](=[O:8])[CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:15][cH:16]1.[NH2:17][c:18]1[cH:19][cH:20][c:21]([F:22])[cH:23][cH:24]1.[Na+:36].[Na+:38].[OH-:37].[OH2:39].[c:25]1([S:26]([OH:27])(=[O:28])=[O:29])[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[F:2][c:3]1[cH:4][cH:5][c:6]([CH:7]([CH:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[NH:17][c:18]2[cH:19][cH:20][c:21]([F:22])[cH:23][cH:24]2)[cH:15][cH:16]1Participants
10
Sources & evidence
- ORD record
- ord-f9f63446acd2488080e377943a8c5326
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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