Triphenylphosphine → 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

HRID 314515Notes

Reaction equation

HRID 314515 reaction equation
[Br:1][c:2]1[c:3]([CH3:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1.[CH3:10][C:11]1([CH3:18])[O:12][BH:13][O:14][C:15]1([CH3:16])[CH3:17].[Pd:19]([Cl:20])[Cl:21].[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1.[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1>>[c:2]1([B:13]2[O:12][C:11]([CH3:10])([CH3:18])[C:15]([CH3:16])([CH3:17])[O:14]2)[c:3]([CH3:9])[cH:4][c:5]([NH2:6])[cH:7][cH:8]1

Participants

5

Reactant 4

HCID 11776Triphenylphosphine2×HCID 233594-Bromo-3-methylanilineHCID 24290Palladium ChlorideHCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane

Product 1

HCID 177502103-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Sources & evidence

ORD record
ord-8c3cc46243fd43a79909728d2cfc2d6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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