Hydrogen Bromide → 3-allyl-2-(2-(dimethylamino)ethylthio)-3H-spiro[benzo[h]quinazoline-5,1'-cyclohexan]-4(6H)-one
Reaction equation
[BrH:25].[CH2:1]([CH:2]=[CH2:3])[n:4]1[c:5](=[S:24])[nH:6][c:7]2[c:12]([c:13]1=[O:14])[C:11]1([CH2:10][c:9]3[c:8]-2[cH:23][cH:22][cH:21][cH:20]3)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[CH3:26][N:27]([CH2:28][CH2:29][Br:30])[CH3:31].[CH3:35][CH2:36][OH:37].[K+:33].[OH-:32].[OH2:34]>>[CH2:1]([CH:2]=[CH2:3])[n:4]1[c:5]([S:24][CH2:29][CH2:28][N:27]([CH3:26])[CH3:31])[n:6][c:7]2[c:12]([c:13]1=[O:14])[C:11]1([CH2:10][c:9]3[c:8]-2[cH:23][cH:22][cH:21][cH:20]3)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c22bc0e6ea144c0b86d453079d206e73
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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