Dichloromethane → 2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-iodo-6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-isobutyramide
Reaction equation
[CH:16]([N:17]([CH2:18][CH3:19])[CH:20]([CH3:21])[CH3:22])([CH3:23])[CH3:24].[Cl:45][CH2:46][Cl:47].[F:25][C:26]([c:27]1[cH:28][c:29]([C:37]([C:38](=[O:39])[Cl:40])([CH3:41])[CH3:42])[cH:30][c:31]([C:33]([F:34])([F:35])[F:36])[cH:32]1)([F:43])[F:44].[I:1][c:2]1[c:3]([NH2:15])[cH:4][n:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:7]1>>[I:1][c:2]1[c:3]([NH:15][C:38]([C:37]([c:29]2[cH:28][c:27]([C:26]([F:25])([F:43])[F:44])[cH:32][c:31]([C:33]([F:34])([F:35])[F:36])[cH:30]2)([CH3:41])[CH3:42])=[O:39])[cH:4][n:5][c:6]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-a392c83e6e5e402ea52f100820101ff4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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