Ethyl Acetate → Methyl 2-(benzyloxycarbonylamino)-2-(1,4-dioxaspiro[4.5]decan-8-ylidene)acetate

HRID 314790Notes

Reaction equation

HRID 314790 reaction equation
[CH2:12]([c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)[O:19][C:20](=[O:21])[NH:22][CH:23]([C:24](=[O:25])[O:26][CH3:27])[P:28]([O:29][CH3:30])([O:31][CH3:32])=[O:33].[CH3:34][N:35]([CH3:36])[C:37]([N:38]([CH3:39])[CH3:40])=[NH:41].[CH3:42][CH2:43][O:44][C:45]([CH3:46])=[O:47].[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][C:8](=[O:11])[CH2:9][CH2:10]2>>[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][C:8](=[C:23]([NH:22][C:20]([O:19][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1)=[O:21])[C:24](=[O:25])[O:26][CH3:27])[CH2:9][CH2:10]2

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 664601,1,3,3-TetramethylguanidineHCID 5674151,4-Dioxaspiro[4.5]decan-8-oneHCID 2734718Methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethyl phosphono)acetate

Product 1

HCID 11256965Methyl 2-(benzyloxycarbonylamino)-2-(1,4-dioxaspiro[4.5]decan-8-ylidene)acetate

Sources & evidence

ORD record
ord-8eb10b0fd4f04c5ea23be215a19c3ed4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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