3-Allyl-4-hydroxybenzonitrile → 3-Allyl-4-benzyloxy-benzonitrile

HRID 31501Notes

Reaction equation

HRID 31501 reaction equation
[CH2:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[OH:12])[C:7]#[N:8])[CH:2]=[CH2:3].[CH2:13](Br)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.C(=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[CH2:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[O:12][CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]#[N:8])[CH:2]=[CH2:3]

Participants

4

Reactant 2

HCID 2584423-Allyl-4-hydroxybenzonitrileHCID 86593042Benzylbromide potassium carbonate

Product 1

HCID 114593413-Allyl-4-benzyloxy-benzonitrile

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 5d from 3-allyl-4-hydroxy-benzonitrile and benzylbromide/potassium carbonate in dimethylformamide.

Sources & evidence

ORD record
ord-ba07be39c12743f09d36ec0f4f56c48a
Source dataset
uspto-grants-2008_09
Patent number
US07425641B2

Reaction notes

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