2,3-Dichloropyridine → 7-(3-Chloropyridin-2-yl)-N-(4-(difluoromethoxy)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine
Reaction equation
[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:22][c:23]1[n:24][cH:25][cH:26][cH:27][c:28]1[Cl:29].[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([NH:10][c:11]2[c:12]3[c:13]([n:14][cH:15][n:16]2)[CH2:17][NH:18][CH2:19][CH2:20]3)[cH:8][cH:9]1)[F:21]>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7]([NH:10][c:11]2[c:12]3[c:13]([n:14][cH:15][n:16]2)[CH2:17][N:18]([c:23]2[n:24][cH:25][cH:26][cH:27][c:28]2[Cl:29])[CH2:19][CH2:20]3)[cH:8][cH:9]1)[F:21]Participants
4
Sources & evidence
- ORD record
- ord-3ac4e3b007954256ae0e67086ad5acc4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…