Triethylamine → N,N-Dimethyl-1H-1,2,4-triazole-1-sulfonamide

Participants

Reaction Conditions

Reaction Steps

Triazole (5.08 g, 73.6 mmol) was dissolved in toluene (80 ml), and thereto were added triethylamine (9.52 ml, 68.4 mmol) and dimethylsulfamoyl chloride (10.6 ml, 73.6 mmol), and the mixture was stirred at 50° C. for 2 hours. The precipitates were removed by filtration, and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography to give the title compound (4.52 g, 38%).

Provenance & Evidence