反应详情

温度

50 °C

Triazole (5.08 g, 73.6 mmol) was dissolved in toluene (80 ml), and thereto were added triethylamine (9.52 ml, 68.4 mmol) and dimethylsulfamoyl chloride (10.6 ml, 73.6 mmol), and the mixture was stirred at 50° C. for 2 hours. The precipitates were removed by filtration, and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography to give the title compound (4.52 g, 38%).

1. customThe precipitates were removed by filtration
2. concentrationthe filtrate was concentrated under reduced pressure
3. customThe resulting residue was purified by silica gel column chromatography