Dichloromethane → prop-2-enyl N-(3-piperidin-4-yl-1H-pyrrolo[3,2-b]pyridin-5-yl)carbamate

HRID 315477Notes

Reaction equation

HRID 315477 reaction equation
[CH2:1]=[CH:2][CH2:3][O:4][C:5](=[O:6])[NH:7][c:8]1[cH:9][cH:10][c:11]2[c:12]([n:13]1)[c:14]([CH:17]1[CH2:18][CH2:19][N:20]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:21][CH2:22]1)[cH:15][nH:16]2.[Cl:37][CH2:38][Cl:39].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[CH2:1]=[CH:2][CH2:3][O:4][C:5](=[O:6])[NH:7][c:8]1[cH:9][cH:10][c:11]2[c:12]([n:13]1)[c:14]([CH:17]1[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]1)[cH:15][nH:16]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 196015485-(N-[prop-1-en-3-yloxycarbonyl]amino)-3-(1-tert-butoxycarbonylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

Product 1

HCID 19601490prop-2-enyl N-(3-piperidin-4-yl-1H-pyrrolo[3,2-b]pyridin-5-yl)carbamate

Sources & evidence

ORD record
ord-eea6958d5dcb477dbe7fa6bff4bea493
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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