Toluene → 5-(1-(4-(trifluoromethyl)phenyl)piperidin-4-yloxy)-2,3-dihydro-1H-inden-1-one
Reaction equation
[CH3:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1.[F:26][C:27]([c:28]1[cH:29][cH:30][c:31]([N:34]2[CH2:35][CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]2)[cH:32][cH:33]1)([F:41])[F:42].[O:12]=[C:13]([O:14][CH:15]([CH3:16])[CH3:17])[N:18]=[N:19][C:20]([O:21][CH:22]([CH3:23])[CH3:24])=[O:25].[OH:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[C:7](=[O:11])[CH2:6][CH2:5]2.[c:43]1([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[cH:57][cH:58][cH:59][cH:60][cH:61]1>>[O:1]([c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[C:7](=[O:11])[CH2:6][CH2:5]2)[CH:37]1[CH2:36][CH2:35][N:34]([c:31]2[cH:30][cH:29][c:28]([C:27]([F:26])([F:41])[F:42])[cH:33][cH:32]2)[CH2:39][CH2:38]1Participants
6
Sources & evidence
- ORD record
- ord-e53eb257b8fa42019c16db99f3c44e9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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