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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 315832Generated: October 30, 2026

Tetrahydrofuran → N-[5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamide

https://huagongshe.com/reaction/315832

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2,4-DichloropyrimidineHCID 77531—
ReactantN-[5-ethynyl-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamideHCID 59511434—
ProductN-[5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-(methyloxy)phenyl]-2,2,2-trifluoroacetamideHCID 59511410—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-9698121597d8431380ea312417e3d0ad
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)