Acetic Acid → 6-Bromo-5-hydroxy-2-isopropoxy-4-(trifluoromethyl)quinoline
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]2[c:11]([C:24]([F:25])([F:26])[F:27])[cH:12][c:13]([O:20][CH:21]([CH3:22])[CH3:23])[n:14][c:15]2[cH:16][cH:17][c:18]1[Br:19].[CH3:34][S:35](=[O:36])(=[O:37])[OH:38].[CH3:39][C:40](=[O:41])[OH:42].[K+:28].[K+:29].[O-:30][C:31]([O-:32])=[O:33].[OH2:43]>>[OH:8][c:9]1[c:10]2[c:11]([C:24]([F:25])([F:26])[F:27])[cH:12][c:13]([O:20][CH:21]([CH3:22])[CH3:23])[n:14][c:15]2[cH:16][cH:17][c:18]1[Br:19]Participants
7
Sources & evidence
- ORD record
- ord-b41df321a5284595b102bcd0ae3fbf20
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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