2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide → 4-Hydroxyproline

HRID 315967Notes

Reaction equation

HRID 315967 reaction equation
[OH:1][CH2:2][CH:3]([CH:4]([c:5]1[cH:6][cH:7][c:8]([N+:9](=[O:10])[O-:11])[cH:12][cH:13]1)[OH:14])[NH:15][C:16]([CH:17]([Cl:18])[Cl:19])=[O:20].[OH:21][C:22](=[O:23])[CH:24]1[CH2:25][CH2:26][CH2:27][NH:28]1>>[OH:1][CH:26]1[CH2:25][CH:24]([C:22]([OH:21])=[O:23])[NH:28][CH2:27]1

Participants

3

Reactant 2

HCID 2982,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamideHCID 614proline dl-form

Product 1

HCID 8254-Hydroxyproline

Sources & evidence

ORD record
ord-50ad6a1ff9154c62a5972c7b591ecd20
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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