Bromide ion → 2-(Cyclopropylsulfonyl)-6-(trifluoromethyl)nicotinic acid

HRID 316428Notes

Reaction equation

HRID 316428 reaction equation
[Br-:7].[CH3:25][S:26](=[O:27])[CH3:28].[CH:1]1([S:4](=[O:5])[O-:6])[CH2:2][CH2:3]1.[Cl:9][c:10]1[c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[n:18]1.[Cu:29][I:30].[Mg+2:8].[Na+:24].[OH-:23].[OH2:31]>>[CH:1]1([S:4](=[O:5])(=[O:6])[c:10]2[c:11]([C:12](=[O:13])[OH:14])[cH:15][cH:16][c:17]([C:19]([F:20])([F:21])[F:22])[n:18]2)[CH2:2][CH2:3]1

Participants

10

Reactant 9

HCID 259Bromide ionHCID 679Dimethyl SulfoxideHCID 888Magnesium CationHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27782102-Chloro-6-(trifluoromethyl)nicotinic acidHCID 20739353Cyclopropanesulfinate

Product 1

HCID 684877982-(Cyclopropylsulfonyl)-6-(trifluoromethyl)nicotinic acid

Sources & evidence

ORD record
ord-eba1c012e26f48c283ea6efb5c355ea0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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