HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2,3-dimethyl-1-oxidopyridin-1-ium → 2-(((4-(2-(2-(Methoxymethyl)-1,3-dioxolan-2-yl)ethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2,3-dimethyl-1-oxidopyridin-1-ium | HCID 9877446 | — |
| Reactant | 2-(2-(Methoxymethyl)-1,3-dioxolan-2-yl)ethanol | HCID 59792568 | — |
| Reactant | 2-(((3-Methyl-4-((8-methyl-1,4,7,9-tetraoxaspiro[4.5]dec-8-yl)methoxy)pyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776550 | — |
| Product | 2-(((4-(2-(2-(Methoxymethyl)-1,3-dioxolan-2-yl)ethoxy)-3-methylpyridin-2-yl)methyl)sulfinyl)-1h-benzimidazole sodium salt | HCID 66776626 | 3.9% |
Reaction Steps
The same procedure as in the steps (5d) to (5h) of Example 5 was repeated using 4-chloro-2,3-dimethylpyridine 1-oxide and 2-(2-(methoxymethyl)-1,3-dioxolan-2-yl)ethanol to obtain the title compound (312 mg, 5 steps 3.9%) as a light yellow foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425634B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-edb0fff28eba4b36bd4723dec06abb69 |
| Source note | uspto-grants-2008_09 |