Ethanol → [5-(5-Amino-2-fluoro-phenyl)-5-difluoromethyl-5,6-dihydro-2H-[1,4]oxazin-3-yl]-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1=[N:13][C:12]([CH:14]([F:15])[F:16])([c:17]2[c:18]([F:26])[cH:19][cH:20][c:21]([N:23]=[N+:24]=[N-:25])[cH:22]2)[CH2:11][O:10][CH2:9]1)=[O:27].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:30][CH2:31][OH:32].[H:28][H:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1=[N:13][C:12]([CH:14]([F:15])[F:16])([c:17]2[c:18]([F:26])[cH:19][cH:20][c:21]([NH2:23])[cH:22]2)[CH2:11][O:10][CH2:9]1)=[O:27]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-40c7e19d54fd4b65970db6be1a993820
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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