Methanol → tert-butyl ({5-[2-fluoro-3-(hydroxymethyl)phenyl]-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl}methyl)methylcarbamate
Reaction equation
[BH4-:34].[CH3:36][OH:37].[F:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]([CH2:24][N:25]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH3:33])[cH:13][n:14]2[S:15](=[O:16])(=[O:17])[c:18]2[cH:19][n:20][cH:21][cH:22][cH:23]2)[cH:4][cH:5][cH:6][c:7]1[CH:8]=[O:9].[Na+:35].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1.[OH2:38]>>[F:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]([CH2:24][N:25]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH3:33])[cH:13][n:14]2[S:15](=[O:16])(=[O:17])[c:18]2[cH:19][n:20][cH:21][cH:22][cH:23]2)[cH:4][cH:5][cH:6][c:7]1[CH2:8][OH:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2514e21a5eac4996adab094ee50bb4aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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