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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 316913Generated: October 29, 2026

Tetrahydrofuran → 8-fluoro-1-[(3-fluoro-4-hydroxycyclohexyl)amino]-5H-pyrido[4,3-b]indole-4-carbonitrile

https://huagongshe.com/reaction/316913

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant1-[(4-{[tert-Butyl(dimethyl)silyl]oxy}-3-fluorocyclohexyl)amino]-8-fluoro-5H-pyrido[4,3-b]indole-4-carbonitrileHCID 59543120—
Product8-fluoro-1-[(3-fluoro-4-hydroxycyclohexyl)amino]-5H-pyrido[4,3-b]indole-4-carbonitrileHCID 59543123—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-985d1c682fbc4eb7936442c0b4f9b403
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)