Tetrahydrofuran → 8-fluoro-1-[(3-fluoro-4-hydroxycyclohexyl)amino]-5H-pyrido[4,3-b]indole-4-carbonitrile
Reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH:7]1[CH:8]([F:30])[CH2:9][CH:10]([NH:13][c:14]2[n:15][cH:16][c:17]([C:28]#[N:29])[c:18]3[nH:19][c:20]4[cH:21][cH:22][c:23]([F:27])[cH:24][c:25]4[c:26]23)[CH2:11][CH2:12]1)([CH3:5])([CH3:31])[CH3:32].[CH2:34]([N+:35]([CH2:36][CH2:37][CH2:38][CH3:39])([CH2:40][CH2:41][CH2:42][CH3:43])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:48][CH2:49][CH3:50].[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[F-:33]>>[OH:6][CH:7]1[CH:8]([F:30])[CH2:9][CH:10]([NH:13][c:14]2[n:15][cH:16][c:17]([C:28]#[N:29])[c:18]3[nH:19][c:20]4[cH:21][cH:22][c:23]([F:27])[cH:24][c:25]4[c:26]23)[CH2:11][CH2:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-985d1c682fbc4eb7936442c0b4f9b403
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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