Hydrochloric Acid → 4-(4-Fluorophenyl)-1-methyl-4-piperidinamine

HRID 316970Notes

Reaction equation

HRID 316970 reaction equation
[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[ClH:18].[ClH:45].[F:19][c:20]1[cH:21][cH:22][c:23]([C:26]2([C:33]([OH:34])=[O:35])[CH2:27][CH2:28][N:29]([CH3:32])[CH2:30][CH2:31]2)[cH:24][cH:25]1.[Na+:37].[OH-:36].[c:1]1([P:2]([c:5]2[cH:6][cH:7][cH:8][cH:9][cH:10]2)(=[O:11])[N:15]=[N+:3]=[N-:4])[cH:12][cH:13][cH:14][cH:16][cH:17]1>>[NH2:15][C:26]1([c:23]2[cH:22][cH:21][c:20]([F:19])[cH:25][cH:24]2)[CH2:27][CH2:28][N:29]([CH3:32])[CH2:30][CH2:31]1

Participants

7

Reactant 6

HCID 313Hydrochloric Acid2×HCID 923Sodium ionHCID 961HydroxideHCID 1140TolueneHCID 199401P,P-Diphenylphosphinic azideHCID 49760795HCID 49760795, compound

Product 1

HCID 497607944-(4-Fluorophenyl)-1-methyl-4-piperidinamine

Sources & evidence

ORD record
ord-deafa959b82f422daee6142458048c50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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