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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 317057Generated: October 25, 2026

Tetrahydrofuran → 4,4,4-Trifluoro-3-hydroxy-3-methyl-1-[4-(1-pyrrolidinylsulfonyl)phenyl]but-1-yne

https://huagongshe.com/reaction/317057

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantMethyl trifluoromethyl ketoneHCID 9871—
Reactant4-(1-Pyrrolidinylsulfonyl)phenylacetyleneHCID 21469119—
ReactantButyllithiumHCID 178418339—
Product4,4,4-Trifluoro-3-hydroxy-3-methyl-1-[4-(1-pyrrolidinylsulfonyl)phenyl]but-1-yneHCID 21469115—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-c6456db642604826b5bd4d69725bb987
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)