Tetrahydrofuran → N-(4-((4,5-dichloro-2-fluorophenyl)amino)quinazolin-6-yl)acrylamide
Reaction equation
[C:1]([CH:2]=[CH2:3])(=[O:4])[Cl:5].[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[Cl:6][c:7]1[cH:8][c:9]([NH:15][c:16]2[n:17][cH:18][n:19][c:20]3[cH:21][cH:22][c:23]([NH2:26])[cH:24][c:25]23)[c:10]([F:14])[cH:11][c:12]1[Cl:13]>>[C:1]([CH:2]=[CH2:3])(=[O:4])[NH:26][c:23]1[cH:22][cH:21][c:20]2[n:19][cH:18][n:17][c:16]([NH:15][c:9]3[cH:8][c:7]([Cl:6])[c:12]([Cl:13])[cH:11][c:10]3[F:14])[c:25]2[cH:24]1Participants
4
Sources & evidence
- ORD record
- ord-48aa6d1e041145e2bcabb572563ada98
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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