Dimethyl Sulfoxide → 4-Chloro-5-{4-[3-(dimethylamino)propoxy]-2,6-difluorophenyl}-6-[(2,2,2-trifluoroethyl)amino]pyrimidin-2-yl(methyl)cyanamide
Reaction equation
[CH3:36][S:37]([CH3:38])=[O:39].[CH3:3][N:4]([CH2:5][CH2:6][CH2:7][OH:8])[CH3:9].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[Cl:10][c:11]1[n:12][c:13]([N:32]([C:33]#[N:34])[CH3:35])[n:14][c:15]([NH:26][CH2:27][C:28]([F:29])([F:30])[F:31])[c:16]1-[c:17]1[c:18]([F:25])[cH:19][c:20]([F:24])[cH:21][c:22]1[F:23].[H-:1].[Na+:2]>>[CH3:3][N:4]([CH2:5][CH2:6][CH2:7][O:8][c:20]1[cH:19][c:18]([F:25])[c:17](-[c:16]2[c:11]([Cl:10])[n:12][c:13]([N:32]([C:33]#[N:34])[CH3:35])[n:14][c:15]2[NH:26][CH2:27][C:28]([F:29])([F:30])[F:31])[c:22]([F:23])[cH:21]1)[CH3:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a1337467ede94b43af3d7d0cde126dff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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