Hydrogen Bromide → (pyridin-2-ylmethyl)-3,4-dihydro-2H-spiro[furo[2,3-h][1,5]benzodioxepine-9,3'-indol]-2'(1'H)-one

HRID 317750Notes

Reaction equation

HRID 317750 reaction equation
[Br:25][CH2:26][c:27]1[n:28][cH:29][cH:30][cH:31][cH:32]1.[Br:33][CH2:34][CH:35]1[CH2:36][CH2:37][CH2:38][CH2:39][O:40]1.[BrH:24].[NH:1]1[C:2](=[O:23])[C:3]2([CH2:4][O:5][c:6]3[c:7]2[cH:8][c:9]2[c:10]([cH:16]3)[O:11][CH2:12][CH2:13][CH2:14][O:15]2)[c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]21>>[N:1]1([CH2:26][c:27]2[n:28][cH:29][cH:30][cH:31][cH:32]2)[C:2](=[O:23])[C:3]2([CH2:4][O:5][c:6]3[c:7]2[cH:8][c:9]2[c:10]([cH:16]3)[O:11][CH2:12][CH2:13][CH2:14][O:15]2)[c:17]2[cH:18][cH:19][cH:20][cH:21][c:22]21

Participants

5

Reactant 4

HCID 260Hydrogen BromideHCID 1419172-(Bromomethyl)tetrahydro-2H-pyranHCID 5642092-(Bromomethyl)pyridineHCID 461939253,4-dihydro-2H-spiro[furo[2,3-h][1,5]benzodioxepine-9,3'-indol]-2'(1'H)-one

Product 1

HCID 46193923(pyridin-2-ylmethyl)-3,4-dihydro-2H-spiro[furo[2,3-h][1,5]benzodioxepine-9,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-cdde51a148ae460da36fb000ab93f66e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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