Tetrahydrofuran → 5-[(4-Phenylphenyl)methyl]-1-(2-trimethylsilylethoxymethyl)pyrrolidin-2-one
Reaction equation
[CH2:20]([Li:21])[CH2:22][CH2:23][CH3:24].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[Cl:25][CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33].[c:1]1(-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][c:4]([CH2:7][CH:8]2[CH2:9][CH2:10][C:11](=[O:13])[NH:12]2)[cH:5][cH:6]1>>[c:1]1(-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:2][cH:3][c:4]([CH2:7][CH:8]2[CH2:9][CH2:10][C:11](=[O:13])[N:12]2[CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:5][cH:6]1Participants
6
Sources & evidence
- ORD record
- ord-46d07fe8d5f84d93a1f07e11e3cf06dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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