HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → [4-(2,4-Dichlorophenyl)-5-piperazinylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 22142789 | HCID 22142789 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [4-(2,4-Dichlorophenyl)-5-piperazinylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine | HCID 9805529 | — |
Reaction Steps
1 mmol of tert-butyl 4-[4-(2,4-dichlorophenyl)-2-({2-[(5-nitro(2-pyridyl))amino]-ethyl}amino)pyrimidin-5-yl]piperazinecarboxylate is heated to 60° C. 3M HCl in MeOH for one hour and concentrated in vacuo to obtain [4-(2,4-dichlorophenyl)-5-piperazinylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425557B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-51038916561e49c192cae502128beeb2 |
| Source note | uspto-grants-2008_09 |