Dimethylformamide → 3-Tert-butyl-5-chloro-4-dimethylaminobenzaldehyde

HRID 318068Notes

Reaction equation

[Br:12][c:13]1[cH:14][c:15]([C:23]([CH3:24])([CH3:25])[CH3:26])[c:16]([N:20]([CH3:21])[CH3:22])[c:17]([Cl:19])[cH:18]1.[CH2:7]([Li:8])[CH2:9][CH2:10][CH3:11].[CH3:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH3:27][N:28]([CH:29]=[O:30])[CH3:31]>>[c:13]1([CH:29]=[O:30])[cH:14][c:15]([C:23]([CH3:24])([CH3:25])[CH3:26])[c:16]([N:20]([CH3:21])[CH3:22])[c:17]([Cl:19])[cH:18]1

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 8058Hexane

HCID 67276978(4-Bromo-2-tert-butyl-6-chlorophenyl)dimethylamine

HCID 178418339Butyllithium

Product 1

HCID 866465713-Tert-butyl-5-chloro-4-dimethylaminobenzaldehyde

Sources & evidence

ORD record: ord-85ff3438ddab427ca81fab2b83da47b9
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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