2,3-Butanediol → 3-[6-Chloro-2-[(2,3-difluorophenyl)methylsulfanyl]pyrimidin-4-yl]oxybutan-2-ol
Reaction equation
[CH3:1][CH:2]([CH:3]([CH3:4])[OH:5])[OH:6].[Cl:7][c:8]1[n:9][c:10]([S:15][CH2:16][c:17]2[c:18]([F:24])[c:19]([F:23])[cH:20][cH:21][cH:22]2)[n:11][c:12]([Cl:14])[cH:13]1.[H-:25].[Na+:26].[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[CH3:1][CH:2]([CH:3]([CH3:4])[O:5][c:12]1[n:11][c:10]([S:15][CH2:16][c:17]2[c:18]([F:24])[c:19]([F:23])[cH:20][cH:21][cH:22]2)[n:9][c:8]([Cl:7])[cH:13]1)[OH:6]Participants
6
Sources & evidence
- ORD record
- ord-a5ee8ef7d4bf4ba8aa1f8e1b61218067
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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