6-Chloro-3-nitropyridin-2-ylamine → [4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]methyl {2-[(5-nitro-6-amino(2-pyridyl))amino]ethyl}amine

HRID 31865Notes

Reaction equation

HRID 31865 reaction equation
[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][C:6]1[N:11]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=2[Cl:19])[C:9]([C:20]2[NH:21][CH:22]=[CH:23][N:24]=2)=[CH:8][N:7]=1.Cl[C:26]1[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[C:28]([NH2:35])[N:27]=1>>[Cl:19][C:13]1[CH:14]=[C:15]([Cl:18])[CH:16]=[CH:17][C:12]=1[C:10]1[C:9]([C:20]2[NH:24][CH:23]=[CH:22][N:21]=2)=[CH:8][N:7]=[C:6]([CH2:5][NH:4][CH2:3][CH2:2][NH:1][C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-:34])=[O:33])=[C:28]([NH2:35])[N:27]=2)[N:11]=1

Participants

3

Reactant 2

HCID 27240356-Chloro-3-nitropyridin-2-ylamineHCID 54421065(2-Aminoethyl)[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]methylamine

Product 1

HCID 69029696[4-(2,4-Dichlorophenyl)-5-imidazolylpyrimidin-2-yl]methyl {2-[(5-nitro-6-amino(2-pyridyl))amino]ethyl}amine

Procedure

Using the procedure described above, reaction of (2-aminoethyl)[4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]methylamine and 2-chloro-5-nitro-6-amino-pyridine were reacted to afford [4-(2,4-dichlorophenyl)-5-imidazolylpyrimidin-2-yl]methyl {2-[(5-nitro-6-amino(2-pyridyl))amino]ethyl}amine.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-f17654e63ab84893baadb6dd5aefced6
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Reaction notes

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