Ammonium → Trifluoroacetic acid

HRID 318700Notes

Reaction equation

HRID 318700 reaction equation
[CH3:8][Si:9]([CH3:10])([CH3:11])[CH2:12][CH2:13][O:37][CH2:38][n:14]1[cH:15][cH:16][c:17]2[c:18]1[n:19][cH:20][n:21][c:22]2-[c:23]1[cH:24][n:25][n:26]([CH:28]2[CH2:29][CH2:30][C:31](=[CH:34][C:35]#[N:36])[CH2:32][CH2:33]2)[cH:27]1.[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[NH4+:39].[OH-:40]>>[F:1][C:2]([C:3](=[O:4])[OH:5])([F:6])[F:7].[nH:14]1[cH:15][cH:16][c:17]2[c:18]1[n:19][cH:20][n:21][c:22]2-[c:23]1[cH:24][n:25][n:26]([CH:28]2[CH2:29][CH2:30][C:31](=[CH:34][C:35]#[N:36])[CH2:32][CH2:33]2)[cH:27]1

Participants

6

Reactant 4

HCID 223AmmoniumHCID 961HydroxideHCID 6422Trifluoroacetic acidHCID 57477975HCID 57477975, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 578812994-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclohexylideneacetonitrile

Sources & evidence

ORD record
ord-15f23559fed7439daf9c7a8a7fa8d9a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…