Bromobenzene → 2-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methyl-pyrimidine

HRID 319267Notes

Reaction equation

HRID 319267 reaction equation
[BH:16]([OH:17])[OH:18].[Br:19][c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1.[Cl:1][c:2]1[n:3][c:4]([CH3:15])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1>>[c:2]1(-[c:24]2[cH:23][cH:22][cH:21][c:20]([Br:19])[cH:25]2)[n:3][c:4]([CH3:15])[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([Cl:14])[cH:12][cH:13]2)[n:7]1

Participants

4

Reactant 3

HCID 7961BromobenzeneHCID 61668Boronic AcidHCID 202255702-Chloro-4-(4-chloro-phenyl)-6-methyl-pyrimidine

Product 1

HCID 574687612-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methyl-pyrimidine

Sources & evidence

ORD record
ord-71cd677d40c146d3af2773bc91b6ac16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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