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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 319631Generated: October 30, 2026

Dichloromethane → N-propan-2-yl-N-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]pyridine-3-sulfonamide

https://huagongshe.com/reaction/319631

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantDiisopropylethylamineHCID 81531—
ReactantPyridine-3-sulfonyl chlorideHCID 3164136—
Reactant1,1,1-Trifluoro-2-[4-[2-[(propan-2-ylamino)methyl]-4-thiophen-2-ylsulfonylpiperazin-1-yl]phenyl]propan-2-olHCID 77148443—
ProductN-propan-2-yl-N-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]pyridine-3-sulfonamideHCID 76462435—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-a328a28d9abd418abb7ec57f365d3a0d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)