Dichloromethane → N-propan-2-yl-N-[[4-thiophen-2-ylsulfonyl-1-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]piperazin-2-yl]methyl]pyridine-3-sulfonamide
Reaction equation
[CH3:55][N:56]([CH3:57])[c:58]1[cH:59][cH:60][n:61][cH:62][cH:63]1.[CH:43]([N:44]([CH2:45][CH3:46])[CH:47]([CH3:48])[CH3:49])([CH3:50])[CH3:51].[Cl:52][CH2:53][Cl:54].[F:1][C:2]([C:3]([CH3:4])([OH:5])[c:6]1[cH:7][cH:8][c:9]([N:12]2[CH:13]([CH2:26][NH:27][CH:28]([CH3:29])[CH3:30])[CH2:14][N:15]([S:18](=[O:19])(=[O:20])[c:21]3[s:22][cH:23][cH:24][cH:25]3)[CH2:16][CH2:17]2)[cH:10][cH:11]1)([F:31])[F:32].[n:33]1[cH:34][c:35]([S:39](=[O:40])(=[O:41])[Cl:42])[cH:36][cH:37][cH:38]1>>[F:1][C:2]([C:3]([CH3:4])([OH:5])[c:6]1[cH:7][cH:8][c:9]([N:12]2[CH:13]([CH2:26][N:27]([CH:28]([CH3:29])[CH3:30])[S:39]([c:35]3[cH:34][n:33][cH:38][cH:37][cH:36]3)(=[O:40])=[O:41])[CH2:14][N:15]([S:18](=[O:19])(=[O:20])[c:21]3[s:22][cH:23][cH:24][cH:25]3)[CH2:16][CH2:17]2)[cH:10][cH:11]1)([F:31])[F:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a328a28d9abd418abb7ec57f365d3a0d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…