Tetrahydrofuran → 1-Pyrimidin-2-yl-4-[(4'-trifluoromethyl-3-biphenylyl)methyl]piperazine
Reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cl:13][CH2:14][c:15]1[cH:16][c:17](-[c:21]2[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]2)[cH:18][cH:19][cH:20]1.[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[n:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([N:7]2[CH2:8][CH2:9][N:10]([CH2:14][c:15]3[cH:16][c:17](-[c:21]4[cH:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[CH2:11][CH2:12]2)[n:3][cH:4][cH:5][cH:6]1Participants
4
Sources & evidence
- ORD record
- ord-bb55f28d0d9f4eacae8b9aa0e03f4a79
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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