Hydrochloric Acid → 3-Methyl-1-[2-methyl-5-(trifluoromethyl)phenyl]sulfonylpiperazine

HRID 319913Notes

Reaction equation

HRID 319913 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][O:34][CH2:35]1.[CH3:1][CH:2]1[N:3]([C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:4][CH2:5][N:6]([S:8](=[O:9])(=[O:10])[c:11]2[c:12]([CH3:21])[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:7]1.[ClH:29]>>[CH3:1][CH:2]1[NH:3][CH2:4][CH2:5][N:6]([S:8](=[O:9])(=[O:10])[c:11]2[c:12]([CH3:21])[cH:13][cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 77158109Tert-butyl 2-methyl-4-[2-methyl-5-(trifluoromethyl)phenyl]sulfonylpiperazine-1-carboxylate

Product 1

HCID 771581053-Methyl-1-[2-methyl-5-(trifluoromethyl)phenyl]sulfonylpiperazine

Sources & evidence

ORD record
ord-169defa5dd1a4fa4b4dddfaca190fa6e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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