Dichloromethane → (4'-Bromomethyl-3',5'-dichloro-biphenyl-4-yl)-(4-trifluoromethyl-piperidin-1-yl)-methanone
Reaction equation
[C:48]([Br:49])([Br:50])([Br:51])[Br:52].[Cl:1][c:2]1[cH:3][c:4](-[c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][CH:22]([C:25]([F:26])([F:27])[F:28])[CH2:23][CH2:24]3)[cH:15][cH:16]2)[cH:5][c:6]([Cl:10])[c:7]1[CH2:8][OH:9].[Cl:53][CH2:54][Cl:55].[c:29]1([P:30]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][cH:42]2)[cH:43][cH:44][cH:45][cH:46][cH:47]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][CH:22]([C:25]([F:26])([F:27])[F:28])[CH2:23][CH2:24]3)[cH:15][cH:16]2)[cH:5][c:6]([Cl:10])[c:7]1[CH2:8][Br:49]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d6b75dd81a714db189163fe9f967bbc1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…