Dichloromethane → 1,2,3,4-Tetrahydro-naphthalene-1-carboxylic acid (2-{1-[2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetyl]-piperidin-4-yl}-thiazol-4-yl)amide
Reaction equation
[CH:26]([N:27]([CH:28]([CH3:29])[CH3:30])[CH2:31][CH3:32])([CH3:33])[CH3:34].[CH:35]1([C:45](=[O:46])[Cl:47])[CH2:36][CH2:37][CH2:38][c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]21.[Cl:48][CH2:49][Cl:50].[NH2:1][c:2]1[n:3][c:4]([CH:7]2[CH2:8][CH2:9][N:10]([C:13]([CH2:14][n:15]3[n:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][c:19]3[CH3:20])=[O:25])[CH2:11][CH2:12]2)[s:5][cH:6]1>>[NH:1]([c:2]1[n:3][c:4]([CH:7]2[CH2:8][CH2:9][N:10]([C:13]([CH2:14][n:15]3[n:16][c:17]([C:21]([F:22])([F:23])[F:24])[cH:18][c:19]3[CH3:20])=[O:25])[CH2:11][CH2:12]2)[s:5][cH:6]1)[C:45]([CH:35]1[CH2:36][CH2:37][CH2:38][c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]21)=[O:46]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-12ecdea135c548a594af2c536fc2e37a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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