Dichloromethane → 5-Phenylmethoxy-2-(1,2,3,6-tetrahydropyridin-4-yl)pyridine

HRID 320065Notes

Reaction equation

HRID 320065 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([C:15]2=[CH:20][CH2:19][N:18]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])[CH2:17][CH2:16]2)[n:13][cH:14]1.[Cl:35][CH2:36][Cl:37].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([C:15]2=[CH:20][CH2:19][NH:18][CH2:17][CH2:16]2)[n:13][cH:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 16094688tert-Butyl 5-(benzyloxy)-3',6'-dihydro[2,4'-bipyridine]-1'(2'H)-carboxylate

Product 1

HCID 160946905-Phenylmethoxy-2-(1,2,3,6-tetrahydropyridin-4-yl)pyridine

Sources & evidence

ORD record
ord-e61531e06d3b4867bb6e87909f70137d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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