Methanol → N-({1-[4-(6-Cyanoamino-pyridin-2-yl)-cyclohexyl]-azetidin-3-ylcarbamoyl}-methyl)-3-trifluoromethyl-benzamide
Reaction equation
[CH3:37][OH:38].[H-:36].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]2[CH2:9][CH2:10][CH:11]([N:14]3[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]4[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]4)=[O:34])[CH2:17]3)[CH2:12][CH2:13]2)[n:7]1.[Na+:35].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]([CH:8]2[CH2:9][CH2:10][CH:11]([N:14]3[CH2:15][CH:16]([NH:18][C:19](=[O:20])[CH2:21][NH:22][C:23]([c:24]4[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]4)=[O:34])[CH2:17]3)[CH2:12][CH2:13]2)[n:7]1)[C:40]#[N:41]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-404689aad3fa4e00ba1d44cc155498b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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