Water → Urea, N-(1,1-dimethylethyl)-N(sup 1)-(5-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-7-yl)-

HRID 320135Notes

Reaction equation

HRID 320135 reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[NH2:26].[CH2:28]([Cl:29])[Cl:30].[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:21]1)[C:7]([c:14]1[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]1)=[N:8][CH2:9][C:10](=[O:13])[N:11]2[CH3:12].[OH2:27]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:21]1)[C:7]([c:14]1[c:15]([F:20])[cH:16][cH:17][cH:18][cH:19]1)=[N:8][CH2:9][C:10](=[O:13])[N:11]2[CH3:12])[C:28]([NH:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:27]

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 6385Tert-ButylamineHCID 922947-Aminoflunitrazepam

Product 1

HCID 3058283Urea, N-(1,1-dimethylethyl)-N(sup 1)-(5-(2-fluorophenyl)-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-7-yl)-

Sources & evidence

ORD record
ord-9624ced2f4ab45db8c45b1b2862db4ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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