HRID32059

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8082

Piperidine

C5H11N

结构：O=Cc1cccc2c1CCC2NC(=O)CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1

HCID86598500

未命名化合物

PRODUCTS

生成物

结构：O=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCc2c(CN3CCCCC3)cccc21

HCID68930956

未命名化合物

PROCEDURE

实验过程

3-(Naphthalen-2-yl-sulfonylamino)-3-phenyl-N-(4-piperidin-1-ylmethyl-indan-1-yl)-propionamide was prepared from N-(4-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide Example 4, Step G and piperidine, using essentially the same procedure described in Example 1, Step H, yielding a white solid. MS (ESI) m/z 568 (M+H)+.

WORKUP

后处理

customyielding a white solid

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-34abbd6512c14bdc9cce57576de710cc
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07425631B2
来源说明: uspto-grants-2008_09

反应 SMILES

[CH:1]([C:3]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:4]=1[CH2:5][CH2:6][CH:7]2[NH:12][C:13](=[O:36])[CH2:14][CH:15]([NH:22][S:23]([C:26]1[CH:35]=[CH:34][C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:27]=1)(=[O:25])=[O:24])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=O.[NH:37]1[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]1>>[CH:27]1[C:28]2[C:33](=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:34]=[CH:35][C:26]=1[S:23]([NH:22][CH:15]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:14][C:13]([NH:12][CH:7]1[C:8]2[C:4](=[C:3]([CH2:1][N:37]3[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]3)[CH:11]=[CH:10][CH:9]=2)[CH2:5][CH2:6]1)=[O:36])(=[O:24])=[O:25]