Piperidine → HCID 11215220, compound

HRID 32062Notes

Reaction equation

HRID 32062 reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][CH:11]=1)[CH:8]([NH:12][C:13](=[O:36])[CH2:14][CH:15]([NH:22][S:23]([C:26]1[CH:35]=[CH:34][C:33]3[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH:27]=1)(=[O:25])=[O:24])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[CH2:7][CH2:6]2)=O.[NH:37]1[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]1>>[CH:27]1[C:28]2[C:33](=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:34]=[CH:35][C:26]=1[S:23]([NH:22][CH:15]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH2:14][C:13]([NH:12][CH:8]1[C:9]2[C:5](=[CH:4][C:3]([CH2:1][N:37]3[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]3)=[CH:11][CH:10]=2)[CH2:6][CH2:7]1)=[O:36])(=[O:24])=[O:25]

Participants

3

Reactant 2

HCID 8082PiperidineHCID 86598501N-(5-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide

Product 1

HCID 11215220HCID 11215220, compound

Procedure

The title compound was prepared from N-(5-formyl-indan-1-yl)-3-(naphthalen-2-yl-sulfonylamino)-3-phenyl-propionamide (Example 5, Step F) and piperidine yielding a white solid. MS (ESI) m/z 568 (M+H)+.

Sources & evidence

ORD record
ord-16870a3d05d34105a9242b1541297441
Source dataset
uspto-grants-2008_09
Patent number
US07425631B2

Reaction notes

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