Acetic Acid → 9-Bromo-5-(N-hydroxy-phenylcarbamoylmethyl)-6,7-dihydro-1H, 5H-pyrido[1,2,3-de]quinoxaline-2,3-dione

HRID 320623Notes

Reaction equation

HRID 320623 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]3[n:6]([c:7](=[O:13])[c:8](=[O:12])[nH:9][c:10]3[cH:11]1)[CH:14]([CH2:17][C:18](=[O:19])[OH:20])[CH2:15][CH2:16]2.[C:29]([O:30][CH2:31][CH3:32])(=[O:33])[CH3:34].[C:35]([OH:36])(=[O:37])[CH3:38].[OH:21][NH:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]3[n:6]([c:7](=[O:13])[c:8](=[O:12])[nH:9][c:10]3[cH:11]1)[CH:14]([CH2:17][C:18](=[O:19])[N:22]([OH:21])[c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1)[CH2:15][CH2:16]2

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 7518N-PhenylhydroxylamineHCID 8857Ethyl AcetateHCID 104723389-bromo-5-carboxymethyl-6,7-dihydro-1H, 5 H-pyrido[1,2,3-de]quinoxaline-2,3-dione

Product 1

HCID 538938859-Bromo-5-(N-hydroxy-phenylcarbamoylmethyl)-6,7-dihydro-1H, 5H-pyrido[1,2,3-de]quinoxaline-2,3-dione

Sources & evidence

ORD record
ord-8e142fd4b1b4446c957a39a1c3ae6f11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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